Effects of Ultrasound Cycloplasty in Glaucoma Patients:6-Month Results From a Prospective Clinical Study

Abstract

Abstract Objectives To explore effects of ultrasound cycloplasty (UCP) in glaucoma patients, aiming to evaluate the efficacy and safety of UCP. Methods Twenty-two glaucoma patients (23 eyes) who received UCP treatment at the Ophthalmology Department of Nanchang First Hospital from July 2020 to September 2022 were selected.Intraocular pressure (IOP), number of anti-glaucoma agents, best corrected visual acuity (BCVA) and eye pain scores of the patients before and 1, 3, 7 days, 1, 3 and 6 months after treatment were recorded.The complications during treatment and after treatment were also observed.The corneal curvature, pupil size, corneal thickness and anterior chamber depth of pentacam before and 1 day, 1 and 6 months after treatment were measured. Results The preoperative IOP, number of anti-glaucoma agents, and eye pain scores were 37.35 ± 13.79 mmHg, average 3.35 ± 1.23 and 4.39 ± 2.15, which were decreased significantly at each time point after UCP treatment (P < 0. 01). The IOP decrease rates were 33.31%, 45.68%, 46.32%, 47.23%, 41.93%, and 48.46%, respectively. The postoperative IOP reduction at 1, 3 and 7 days, 1, 3 and 6 months were significantly correlated with preoperative IOP (r = 0.719, 0.750, 0.797, 0.661,0.515 and 0.607, all P < 0.05). No serious complication was observed throughout the treatment and the follow-up.There was a temporary change in anterior keratometry 1 day after UCP treatment. BCVA, pupil diameter, corneal thickness and anterior chamber depth remained unchanged. Conclusion UCP was demonstrated to be effective in decreasing IOP, IOP-lowering medications and pain scores in patients with glaucoma. It’s well-tolerated without intraoperative or postoperative complications.