Dynamic X-ray Microtomography vs. Laser-Doppler Vibrometry: A Comparative Study-Reference-Cited by-同舟云学术

Dynamic X-ray Microtomography vs. Laser-Doppler Vibrometry: A Comparative Study

Published:2024-08-08 Issue: Volume: Page:
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Author:

Ivanovic Aleksandra¹^ORCID,Cheng Jeffrey Tao²^ORCID,Schmeltz Margaux³^ORCID,Schlepütz Christian M.³^ORCID,Bonnin Anne³^ORCID,Anschuetz Lukas⁴^ORCID

Affiliation:

1. Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, Switzerland, 2Hearing Research Laboratory, ARTORG Center for Biomedical Engineering Research, University of Bern, Switzerland, Paul Scherrer Institut, Swiss Light Source, Villigen PSI, Switzerland,

2. Department of Otolaryngology, Head and Neck Surgery, Mass. Eye and Ear, Boston Children Hospital, Harvard Medical School, Boston, 02114, MA, USA

3. Swiss Light Source, Paul Scherrer Institut, Villigen PSI, Switzerland

4. Department of Otorhinolaryngology, Head and Neck Surgery, CHUV Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland

Abstract

Purpose: There are challenges in understanding the biomechanics of the human middle ear, and established methods for studying this system show significant limitations. In this study, we evaluate a novel dynamic imaging technique based on synchrotron X-ray microtomography designed to assess the biomechanical properties of the human middle ear by comparing it to laser-Doppler vibrometry (LDV). Methods: We examined three fresh-frozen temporal bones (TB) using dynamic synchrotron-based X-ray microtomography for 256 Hz and 512 Hz, stimulated at 110 dB and 120 dB SPL. In addition, we performed measurements on these TBs using 1D LDV, a well-established method. Results: The normalized displacement values (µm/Pa) at the umbo and the posterior crus of the stapes are consistent or within 5-10 dB differences between all LDV and dynamic microtomography measurements and previously reported literature references. In general, the overall behavior is similar between the two measurement techniques. Conclusion: In conclusion, our results demonstrate the suitability of dynamic synchrotron-based X-ray microtomography in studying the middle ear’s biomechanics. However, this study shows that better standardization regarding acoustic stimulation and measurement points is needed to better compare the two measurement techniques.

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

National Institutes of Health

Publisher

Springer Science and Business Media LLC

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