Abstract
Stroke is the second leading cause of death worldwide. The incidence of stroke in China is the highest in the world. Numerous studies have confirmed the clinical value of the SIRI, SII, NHR, NLR, PLR and MLR in predicting the prognosis of acute ischaemic stroke (AIS) patients. To date, no studies have compared the predictive value of these six composite inflammatory markers. A total of 264 AIS patients with symptoms for < 24 h were included in this study. The short-term prognosis of AIS patients at 30 days was assessed using the modified Rankin scale (mRS), with an mRS score > 2 defined as a poor prognosis. The results of the univariate analysis showed that all six composite inflammatory indices, the SIRI, SII, NHR, NLR, PLR and MLR, were associated with a poor prognosis in patients with AIS. The results of the correlation analysis showed that all six composite inflammatory indicators correlated with the short-term prognosis of AIS patients. The six composite inflammation indicators were included in the binary logistic regression, and the results showed that the SIRI, NLR and PLR were found to be independent risk factors for poor short-term prognosis in AIS patients. Among the six inflammatory markers, the SIRI, NLR and PLR were the most clinically valuable for predicting the short-term prognosis of patients with AIS. Peripheral blood indices are easy to obtain clinically and can provide important clinical value for early prognosis and treatment adjustment.