The Impact of 4% Articaine on ECG: Insights from a Randomised Control Trial

Abstract

Abstract AIM AND BACKGROUND OF THE STUDY Articaine can be used as alternative drug of choice for lignocaine because it has rapid onset and longer duration of action so these qualities of articaine can be beneficial for patient travelling from long distance in which patient can be free from pain. The aim of this study is to Compare the efficacy and safety such as blood pressure and pulse rate ,ECG of the both of 4% Articaine with 1:100,000 epinephrine and 2% Lignocaine with 1:100,000 epinephrine in patients operated for mandibular third molar impaction. METHOD This is a randomized controlled clinical trial a total 30 subjects were participated in the study with age ranging from 22-45 years and parameters such as Drug volume(ml) ,Duration of surgical procedure, Intra operative pain evaluation, Onset of anesthesia, Duration of anesthesia, Duration of postoperative analgesia, ECG,blood pressure,pulse,spo2,temperature were assessed . Results: It was evident that 4% articaine has longer duration of action and great postoperative analgesia in terms of 2% lignocaine and there was no significant difference in ECG,blood pressure,pulse ,spo2,temperature Conclusion It was established that 4% articaine is more effective than 2% lignocaine. Hence might be thought of as a lignocaine substitute in clinical settings.A local anaesthetic solution that is efficient enough to produce sufficient anaesthesia while causing minimal problems is essential for minor oral surgical procedures