Rhinocerebral mucormycosis secondary to acute lymphoblastic leukemia: a case report

Author:

Li Chunmiao1ORCID,Yi Huanhuan1,Wei Bei1,Song Dandan1,Han Fugen1,Seng Dongjie1,Zhao Jing2ORCID

Affiliation:

1. Henan Children's Hospital: Zhengzhou Children's Hospital

2. Beijing Children's Hospital Capital Medical University

Abstract

Abstract Case presentation An 8-year-old boy was admitted to the Department of Hematology and Oncology of Henan Children’s Hospital on January 25, 2021, with generalized fatigue and pallor for 3 weeks. He was diagnosed with rhinocerebral mucormycosis (RCM) secondary to childhood acute lymphoblastic leukemia. He was put on medication, and a surgical debridement was performed. The patient was followed up for treatment. Objective: This study aimed to improve the understanding of RCM secondary to childhood acute lymphoblastic leukemia (ALL). Methods: The clinical data of a patient with RCM secondary to ALL admitted to Henan Children’s Hospital in January 2021 were analyzed, and relevant literature was reviewed. Result: RCM secondary to ALL is rare and difficult to diagnose and has a suboptimal prognosis. Conclusions: For fever, nasal mucosal ulceration, and formation of black scab skin in the nasal cavity and oral mucosa in ALL, the possibility of hair mold infection should be considered. Antifungal drugs and surgical treatment should be started as soon as possible.

Publisher

Research Square Platform LLC

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