Typhoid fever in a rare form caused by eating overripe pineapple: A Case Report and Literature Review

Abstract

Abstract Typhoid fever is an acute infection caused by Salmonella typhi, especially when it is waterborne or foodborne. Overripe pineapple causes typhoid fever because overripe pineapple is a desirable host for the survival of Salmonella typhi. The importance of typhoid fever as a public health burden is reduced by early detection and appropriate antibiotic treatment. A 26-year-old black African male health care worker was admitted to the clinic on July 21, 2022, with a significant chief complaint of headache, loss of appetite, and watery diarrhea. The admitted patient presented with a two-day history of hyperthermia, headache, loss of appetite, and watery diarrhea, as well as back pain, joint weakness, and insomnia. The H antigen titer was positive, which was 1: 189 greater than the normal range and showed the past history of Salmonella typhi infection. The O antigen titer value detected was a false negative result because it was done before the 7-day onset of fever. On admission, ciprofloxacillin 500 mg was given orally twice a day for seven days to treat typhoid by inhibiting the deoxyribonucleic acid replication of Salmonella typhi by preventing Salmonella typhi deoxyribonucleic acid topoisomerase and deoxyribonucleic acid gyrase. Typhoid fever pathogenesis is based on pathogenic factors, infecting species, and host immunity. By using the agglutination biochemical test, the Widal test was able to identify the patient's bloodstream as carrying the salmonella typhi bacteria that causes typhoid fever. Due to contaminated food or unsafe drinking water sources, typhoid fever is associated with travel to developing nations.