Salivary Alpha-Amylase (sAA) Concentration Related to Fatigue Biomarkers in Palm Oil Offiffice Workers in Jambi Province: Preliminary Study

Abstract

Abstract Background The use of Salivary alpha-amylase (sAA) has the potential as a biological sign of work-related fatigue caused by stress and mental workload. This study aimed to determine the levels of sAA and the factors that influence it. Methods This study used a cross-sectional design with a sample of 40 office staff respondents at PT XYZ (Persero). Measurements were made to determine work-related fatigue, mental workload, and sleep quality. Meanwhile, the measurement of basic sAA levels was carried out using the sandwich ELISA method using the Bioenzy® Kit Assay. Results Results of the descriptive analysis showed that workers were dominated by men by 75% with high education level and marital status of 72.5%. Mental Workload Scoring with NASA-TLX shows an average score of 70.91 which is categorized as high workload. Analysis with Pearson correlation showed that the variables of work-related fatigue and sleep quality were significantly correlated with sAA concentration. The final model showed that the work-related fatigue variable indicated that for each one-unit increase in work-related fatigue, the sAA (U/mL) concentration will increase by 15.901 (U/mL). While the sleep quality variable showed the result that for every unit increase in sleep quality, the sAA concentration will decrease by 13.38 (U/mL). Conclusion sAA concentration can be used as a potential candidate for biological markers related to sleep quality and work-related fatigue