Utility of Oxygen Saturation Index (Osi) Over Oxygenation Index (Oi) in Monitoring of Neonates with Respiratory Diseases

Abstract

Abstract Background: -Respiratory diseases is associated with increased risk of mortality, morbidity and worse neurological outcomes. OI is routinely used as an indicator of severity of respiratory disease in neonates. Study aims to find a non-invasive indicator. Aims and objectives : To evaluate the correlation of oxygen saturation index and oxygenation index among the term and preterm neonates with respiratory diseases who meets the inclusion criteria. Materials & Methods : It is a Prospective observational study, conducted at tertiary care NICU , 50 neonates , both preterm and term neonates , who met inclusion criteria were enrolled . Paired samples of OI and OSI were compared. Results : Pearson’s correlation coefficient was calculated to be 0.491 and was statistically significant (p<0.001). This shows significant positive correlation between OI and OSI. Based on the above we propose a regression equation to calculate OS based on given OSI or vice versa, as OSI = 0.391*OI+4.2341 Conclusion : OSI (non invasive measure ) has positive correlation with OI (invasive measure) in neonates with respiratory disease. It can be used to monitor the severity of lung disease thereby preventing sepsis and iatrogenic anemia.