Abstract
Background
To investigate the influence of preoperative noninvasive indexes on surgical outcomes of benign prostatic hyperplasia (BPH) patients and to establish a clinical prediction model.
Methods
A total of 250 cases of BPH patients treated with transurethral resection of the prostate (TURP) in our center from December 2020 to June 2023 were included. The evaluation was completed by detailed history questionnaire, an international prostate symptom score (IPSS) assessment, and a urological ultrasonography.
Results
Among included patients, 185 had effective outcomes and 65 had ineffective outcomes, with an effective rate of 74%. Univariate and multivariate analyses identified international prostatic symptom score-voiding/storage subscore ratio (IPSS-V/S), postvoid residual urine ratio (PVR-R), disease duration, IPP, history of diabetes, history of urinary retention, as independent predictive factors of surgical outcomes, which were further subjected to construct the prediction model. Receiver operating characteristic curve indicated an area under curve of 0.894. The sensitivity and specificity of the model were 79.46% and 87.69%, respectively. Internal validation and the calibration curve indicated good agreement between the predicted outcome and the actual outcome. Clinical decision curves found that the model had a greater net clinical benefit than the "all-intervention" and "no-intervention" scenarios.
Conclusion
The results suggested that BPH patients with a shorter disease duration, a larger IPSS-V/S, a larger IPP, a smaller PVR-R, and no history of diabetes or urinary retention were more likely to have a better outcome after TURP.