Abstract
Background: Aortic regurgitation with dilated annulus presents a challenge for conventional transcatheter aortic valve implantation (TAVI) procedures.
Case presentation: In this unique case, we report an 84 year old frail patient with a history of breathlessness found to have severe aortic regurgitation and moderately impaired left ventricular systolic function. The patient underwent a successful TAVI procedure using the XL-Myval 32 mm transcatheter heart valve (THV) via an anterior right mini-thoracotomy with a direct aortic approach. Remarkably, the patient showed favourable post-procedural progress. Conclusions: This first in human case highlights the efficacy and potential of applying innovative approaches, such as the new sizes of Myval THV and direct aortic access via anterior right mini thoracotomy, in addressing challenging anatomical variations in TAVI procedures with good outcome.