Evaluation of Ovarian Reserve in Unexplained Infertile Cases : A case controlled study

Abstract

Abstract Background The aim of this study was to evaluate the effectiveness of current ovarian reserve tests in unexplained infertile cases. Material And Methods This case-control study was conducted on 70 unexplained infertile women were included in Tertiary Iniversity hospital. Both groups of basal FSH, estradiol, Antimullerian hormone (AMH), inhibin B, ovarian volume, total antral follicle count (AFC), ovarian volume, ovarain stromal blood flow (Peak systolic velocity (PSV), S/D (systole and diastole ratio), Resistance index (RI) and pulsatility index (PI)) values were compared. Results The mean AMH, inhibin B, PSV and stromal blood flow values of the control group patients was higher than those in unexplained infertility group. However, the values of means of RI and PI of the cases in the control were lower than those in infertility group. When PI's value was ≥ 2.00, its sensitivity was 65.7%, and its specificity was 64.3%. In case of the RI's value was ≥ 0.745, its sensitivity was 65.7%, and its specificity was 62.9%. In order to show ovarian reserve in unexplained infertile cases, the sensitivity values can be sorted from high to low as follows : PI > RI > estradiol > FSH > ovarian volume > AFC > inhibin B > stromal blood flow > PSV > S/D. Conclusion In the unexplained infertile patient group with a normal ovarian reserve test results, basal estradiol, decreased PI and RI values may be used as goog ovarian reserve predictors.