Affiliation:
1. Vittore Buzzi Children's Hospital: Ospedale dei Bambini Vittore Buzzi
2. Centro Cardiologico Monzino IRCCS: Centro Cardiologico Monzino Istituto di Ricovero e Cura a Carattere Scientifico
3. Ospedale Maggiore di Milano Policlinico: Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Abstract
Abstract
Background: Pediatric obesity is a global emerging burden for society; among its health-related consequences there are hypertension (HTN) and left ventricular hypertrophy (LVH). Several anthropometric indices have been investigated for the early identification of cardiovascular risk in children. The aim of the present study was to assess whether tri-ponderal mass index (TMI) was associated with LVH in a cohort of obese Caucasian children and adolescents.
Methods: In this observational study, 63 obese children and adolescent aged 7-to-16 years were enrolled. During outpatient visits, adiposity, and cardio-metabolic indices (BMI z-score, WHR, TMI, ABSI) were collected. All subjects underwent a 24-hour ambulatory blood pressure monitoring (ABPM) and transthoracic echocardiography.
Results: Obese children and adolescents with LVH had significantly higher BMI z-score (p=0.009), WHR (p=0.006) and TMI (p=0.026) compared to children without LVH. WHR was the only index significantly correlated with left ventricular mass index (LVMI) (p 0.017).
Conclusion: Left ventricular remodeling is associated with the cardio-metabolic risk marker WHR, but not with the adiposity index TMI among obese children.
Publisher
Research Square Platform LLC