Affiliation:
1. Klinički centar Srbije, Klinika za neurologiju, Beograd
Abstract
Introduction. Superficial siderosis (SS) is caused by chronic subarachnoid
bleeding and is characterized by free iron and hemosiderin deposition along
the pial and subpial structures of central nervous system. SS leads to
progressive and irreversible CNS damage. The most common causes of chronic
subarachnoidal bleeding are tumors, head and spinal cord trauma,
arteriovenous malformations and aneurysms. SS is characterized by clinical
triad: sensorineural hearing loss, cerebellar ataxia and piramydal signs.
Brain MR imaging is the investigation of choice for the diagnosis of SS.
Typical findings include hypointensities seen on T2?weighted MR imaging
around the brain, cerebellum, brain stem, spinal cord, VIII cranial nerve and
atrophy of cerebellum and medulla. Case Outline. A 71-year?old female patient
noticed hand tremor in the middle of the third decade of life, and later
slowly progressive bilateral hearing loss. At the age of 64 she developed un?
steady gate, hand clumsiness and dysarthria, to became incapable of
independent walking and standing five years later. Clinical course and brain
MRI findings were typical for SS, but additional investigation did not reveal
the couse of subarahnoidal bleeding. Conclusion. SS represents a rare and
under?recognized condition that must be considered in all patients with
cerebellar syndrome of unknown cause. Early diagnosis of SS in some cases
with identified cause of chronic bleeding allowes therapeutic interventions
that may prevent further progression of the disease.
Funder
Ministry of Education, Science and Technological Development of the Republic of Serbia
Publisher
National Library of Serbia
Cited by
1 articles.
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