Facile synthesis of water-soluble curcumin nanocrystals

Author:

Markovic Zoran1ORCID,Prekodravac Jovana1ORCID,Tosic Dragana1ORCID,Holclajtner-Antunovic Ivanka2,Milosavljevic Momir1ORCID,Dramicanin Miroslav1ORCID,Todorovic-Markovic Biljana1

Affiliation:

1. Vinča Institute of Nuclear Sciences, Belgrade

2. Faculty for Physical Chemistry, Belgrade

Abstract

In this paper, facile synthesis of water soluble curcumin nanocrystals is reported. Solvent exchange method was applied to synthesize curcumin nanocrystals. Different techniques were used to characterize the structural and photophysical properties of curcumin nanocrystals. We found that nanocurcumin prepared by this method had good chemical and physical stability, could be stored in the powder form at room temperature, and was freely dispersible in water. It was established that the size of curcumin nanocrystals was varied in the range of 20-500 nm. Fourier transform infrared spectroscopy and UV-Vis analyses showed the presence of tetrahydrofuran inside the curcumin nanocrystals. Also, it was found that nanocurcumin emitted photoluminescencewith yellow-green colour.

Funder

Ministry of Education, Science and Technological Development of the Republic of Serbia

Publisher

National Library of Serbia

Subject

General Chemistry

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