Affiliation:
1. Bashkir State Medical University
2. Kuban State Medical University
3. Regional Clinical Hospital No. 2
Abstract
In recent years, there has been an upward trend in the urolithiasis incidence worldwide and an increase in the recurrence of stone formation. Urolithiasis prevalence rates range from 1% to 20%. In some countries, there is an increase in rates up to 37%. Stones are classified into those caused by infections, non infectious causes, and genetic diseases. Alteration in urine microbiome plays a significant role in the infection stone formation. Our objective was to review the current literature on the role of bacteria in the formation of kidney concrements. The gained knowledge could be used to explore new possibilities and improve the understanding of stone formation. We analyzed articles on the composition of the urine microbiome and kidney stones.
Publisher
Scientific Research Institute - Ochapovsky Regional Clinical Hospital No 1
Reference39 articles.
1. Russian Society of Urology. Clinical Guidelines. Urolithiasis. Russian Society of Urologists; 2019. (In Russ.).
2. Kaprin AD, Apolikhin OI, Sivkov AV, et al. The incidence of urolithiasis in the Russian Federation from 2005 to 2020. Experimental and Clinical Urology. 2022;15(2):10–17. (In Russ.). https://doi.org/10.29188/2222-8543-2022-15-2-10-17
3. Türk C, Neisius A, Petrik A, et al. EAU Guidelines on Urolithiasis. European Association of Urology; 2020.
4. Thorleifsson G, Holm H, Edvardsson V, et al. Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density. Nat Genet. 2009;41(8):926–930. PMID: 19561606. https://doi.org/10.1038/ng.404
5. Yang Y, Miao L, Lu Y, Wang S. The genetics of urinary microbiome, an exploration of the trigger in calcium oxalate stone. Front Genet. 2023;14:1260278. PMID: 37854058. PMCID: PMC10579592. https://doi.org/10.3389/fgene.2023.1260278