QSAR of Cytochrome P450
Author:
Affiliation:
1. Department of Chemistry, Pomona College, Claremont, California, 91711, USA
Publisher
Informa UK Limited
Subject
Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics
Link
https://www.tandfonline.com/doi/pdf/10.1081/DMR-120028428
Reference53 articles.
1. The true hydrophobicity of microsomal cytochrome P-450 in the rat. Size dependence of the free energy of binding of a series of hydrocarbon substrates from the aqueous phase to the enzyme and to the membrane as derived from spectral binding data.
2. Rat liver microsomal cytochrome P450-dependent oxidation of 3,5-disubstituted analogues of paracetamol
3. On the mechanism of action of cytochrome P-450. Spectral intermediates in the reaction of P-450LM2 with peroxy compounds.
4. On the mechanism of action of cytochrome P-450. Evaluation of homolytic and heterolytic mechanisms of oxygen-oxygen bond cleavage during substrate hydroxylation by peroxides.
5. The Electron-Transfer Reactions of NADPH-Cytochrome P450 Reductase with Nonphysiological Oxidants
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