Novel and Efficient Method to Synthesize N‐Benzyl‐4‐Formyl‐Piperidine
Author:
Affiliation:
1. a Zhejiang University, Department of Medicinal Chemistry, School of Pharmaceutical Science , Hangzhou, 310031, P. R. China
Publisher
Informa UK Limited
Subject
Organic Chemistry
Link
https://www.tandfonline.com/doi/pdf/10.1081/SCC-200030987
Reference10 articles.
1. Synthesis and Structure-Activity Relationships of Acetylcholinesterase Inhibitors: 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine Hydrochloride and Related Compounds
2. Sugimoto , H. Tsuchiya , Y. and Higurashi , K. Cyclic amine compounds and pharmaceutical use. US Patent 5,100,901. Mar 31, 1992.
3. A New Synthesis of Aldehydes from Ketones Utilizing Trimethylsilyldiazomethane
4. Modified Sodium Bis[2-methoxyethoxy]aluminum Hydride Reagents for the Partial Reduction of Lactones and Esters
5. Large scale synthesis of N-benzyl-4-formylpiperidine through partial reduction of esters using aluminum hydride reagents modified with pyrrolidine
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1. Synthetic Approaches for Piperidone-Based Templates as Scaffolds to Access Chirally Enriched Donepezil Analogues;ACS Omega;2020-02-03
2. Introduction;Piperidine-Based Drug Discovery;2017
3. Industrially Viable Preparation ofN-Benzyl-4-formylpiperidine, a Key Intermediate of Donepezil;Organic Preparations and Procedures International;2013-03-04
4. Synthesis and biological evaluation of novel piperidin-4-ol derivatives;Monatshefte für Chemie - Chemical Monthly;2011-09-24
5. Regioselective synthesis of 2,3-dihydrospiro[1,4]dioxino[2,3-b]pyridine derivatives;Tetrahedron Letters;2010-08
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