SIMPLIFIED PROCEDURE FOR THE DETERMINATION OF CODEINE AND ITS METABOLITE IN URINE AND PLASMA BY LC/UV AND LC/MS USING MIXED-MODE CATION EXCHANGE FOR SAMPLE PREPARATION

Author:

Cheng Yung-Fong1,Neue Uwe D.1,Bonin Robert1,Block Eric1,Bean Laura1

Affiliation:

1. a Waters Corporation , 34 Maple Street, Milford, MA, 01757, U.S.A.

Publisher

Informa UK Limited

Subject

Clinical Biochemistry,Pharmaceutical Science,Biochemistry,Analytical Chemistry

Reference12 articles.

1. Jaffe , J. H. and Martin , W. R. 1985.Goodman and Gilman's The Pharmacological Basis of TherapeuticsEdited by: Rall , T. W. and Murad , F. 491–531. New York: Macmillan.

2. Plasma codeine and morphine concentrations after therapeutic oral doses of codeine-containing analgesics

3. Quantitative GLC Determination of Codeine in Plasma

4. Assay for codeine, morphine and ten potential urinary metabolites by gas chromatography—mass fragmentography

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