Epigenetic Therapy in a Rare Ovarian Cancer — A Double-Edged Sword
Author:
Affiliation:
1. Memorial Sloan Kettering Cancer Center, New York, NY
Publisher
Massachusetts Medical Society
Link
http://www.nejm.org/doi/pdf/10.1056/NEJMc2407971
Reference5 articles.
1. Recurrent SMARCA4 mutations in small cell carcinoma of the ovary
2. Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics
3. The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type
4. Tazemetostat in advanced epithelioid sarcoma with loss of INI1/SMARCB1: an international, open-label, phase 2 basket study
5. EZH2 inhibition by tazemetostat: mechanisms of action, safety and efficacy in relapsed/refractory follicular lymphoma
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