1. From the Departments of Medicine (F.P.C., Y.-B.C., S.B.), Pathology (S.G.S.), and Pediatrics (F.A.H.), Massachusetts General Hospital, and the Departments of Medicine (F.P.C., Y.-B.C., S.B.), Pathology (S.G.S.), and Pediatrics (F.A.H.), Harvard Medical School — both in Boston.