1. Residues 1-5, which remain disordered in all available PIC structures, are modeled in a random conformation for display purposes only. eIF1A-CTT, which remains disordered in the PIC, is not shown. eIF1 (green) is shown in surface representation. eIF2?, ?, and ? are shown as yellow, gold, and orange ribbon, respectively. The eIF1-binding helix of eIF3c is red. The mRNA is violet, and the initiator tRNA is purple. The rest of the 43S PIC components, including the 40S ribosomal subunit rRNA and proteins, are shown as semitransparent ribbon;Yi;(B) Cross-eye stereo view of eIF1A within the 48S PIC, 7qp6.pdb,2020
2. Interaction between eukaryotic initiation factors 1A and 5B is required for efficient ribosomal subunit joining;M G Acker;The Journal of biological chemistry,2006
3. Kinetic analysis of late steps of eukaryotic translation initiation;M G Acker;J Mol Biol,2009
4. A multifactor complex of eukaryotic initiation factors, eIF1, eIF2, eIF3, eIF5, and initiator tRNA(Met) is an important translation initiation intermediate in vivo;K Asano;Genes & development,2000
5. Conserved bipartite motifs in yeast eIF5 and eIF2Bepsilon, GTPase-activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2;K Asano;The EMBO journal,1999