Use of etorphine-acepromazine and diprenorphine in reversible neuroleptanalgesia of rats

Abstract

The death rate due to neuroleptanalgesia (0·35%) was significantly lower than for barbiturate anaesthesia (1·59%). Complications were few even when animals received multiple, repeated, anaesthesia, and depth of anaesthesia could be adjusted easily. Further, it could effectively be reversed within minutes by the specific antagonist diprenorphine.