In vitro Researches into the Biocompatibility of Titanium Alloys with a Modifi ed Surface

Author:

Еshkulov U. E.1,Tarbokov V. A.2,Ivanov S. Yu.3,Nochovnaya N. A.4,Dymnikov A. B.1,Alymbaev R. S.5

Affiliation:

1. The Peoples’ Friendship University of Russia

2. National Research Tomsk Polytechnic University

3. The Peoples’ Friendship University of Russia; First Moscow State Medical University named after I.M. Sechenovof the Ministry of Health care of Russia (Sechenov University);

4. All-Russian Scientific Research Institute of Aviation Materials

5. Scientific and Production Association «Preventive Medicine»

Abstract

This work presents the results of a comparative in vitro study into the biocompatibility of titanium samples, the surface of which was pre-treated using various methods: milling, machining with acid etching and irradiation with a powerful ion beam (PIB) for creating a relief with the required roughness and the shape of asperities. A study of the effectiveness of attachment and growth of Balb/NIH 3T3 fi broblasts on titanium products with various types of surface treatment demonstrated that irradiation of a titanium surface with a powerful ion beam (PIB) leads to its active colonization with cells having a fl attened and stellate shape, which confi rms their active growth. An assessment of migration of metal impurities from the titanium alloy VT 1-0 was evaluated using the x-ray fl uorescence method

Publisher

Scientific Center for Biomedical Technologies of the Federal Medical-Biological Agency

Subject

General Medicine

Reference18 articles.

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Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Biocompatibility of an interspinous implant made of titanium alloys;Pediatric Traumatology, Orthopaedics and Reconstructive Surgery;2022-12-25

2. Micro X-ray Spectral Analysis and Comprehensive In Vivo Study of Modified Titanium Implants;Bulletin of Experimental Biology and Medicine;2022-08

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