Affiliation:
1. Institut Pasteur, Université Paris Cité, CNRS UMR 3691, Membrane Traffic and Pathogenesis 1 , F-75015 Paris , France
2. Université Paris-Saclay 2 , 91190 Gif-sur-Yvette , France
Abstract
ABSTRACT
Actin-based protrusions are at the base of many fundamental cellular processes, such as cell adhesion, migration and intercellular communication. In recent decades, the discovery of new types of actin-based protrusions with unique functions has enriched our comprehension of cellular processes. However, as the repertoire of protrusions continues to expand, the rationale behind the classification of newly identified and previously known structures becomes unclear. Although current nomenclature allows good categorization of protrusions based on their functions, it struggles to distinguish them when it comes to structure, composition or formation mechanisms. In this Cell Science at a Glance article, we discuss the different types of actin-based protrusions, focusing on filopodia, cytonemes and tunneling nanotubes, to help better distinguish and categorize them based on their structural and functional differences and similarities.
Funder
Fondation pour la Recherche Médicale
Agence Nationale de la Recherche
Institut Pasteur
Publisher
The Company of Biologists
Cited by
2 articles.
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