InvestigatingC. elegansdevelopment through mosaic analysis-Reference-Cited by-同舟云学术

InvestigatingC. elegansdevelopment through mosaic analysis

Published:2003-10-15 Issue:20 Volume:130 Page:4761-4768
ISSN:1477-9129
Container-title:Development
language:en
Short-container-title:

Author:

Yochem John¹,Herman Robert K.¹

Affiliation:

1. Department of Genetics, Cell Biology and Development, University of Minnesota, 6-160 Jackson Hall, 321 Church Street, Minneapolis, MN 55455,USA

Abstract

The analysis of genetically mosaic worms, in which some cells carry a wild-type gene and others are homozygous mutant, can reveal where in the animal a gene acts to prevent the appearance of a mutant phenotype. In this primer article, we describe how Caenorhabditis elegans genetic mosaics are generated, identified and analyzed, and we discuss examples in which the analysis of mosaic worms has provided important information about the development of this organism.

Publisher

The Company of Biologists

Subject

Developmental Biology,Molecular Biology

Link

http://journals.biologists.com/dev/article-pdf/130/20/4761/1144687/4761.pdf

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