Anticancer Effect of Aristolochia tagala and Curcuma caesia Acting Through Tumor Necrosis Factor-α

Author:

Hadem Khetbadei Lysinia Hynniewta1,Kma Lakhon1,Sharan Rajeshwar N.1ORCID,Sen Arnab2

Affiliation:

1. North Eastern Hill University, India

2. Indian Council of Agricultural Research, Research Center for North East Region, India

Abstract

This chapter begins with a brief description of the events associated with carcinogenesis such as what led a normal cell to transform into a pre-neoplastic one, their multiplication, and development into cancer. The authors also described how reactive oxygen species (ROS) are generated endogenously and from carcinogens, their role in carcinogenesis, and the link between inflammation and cancer. Elucidation of how cancer arises contributes to understanding the molecular mechanisms of action of some natural products. Herbal natural products contain metabolites that exert a physiological action on human body. These metabolites are used therapeutically in modern medical practices to prevent and cure various diseases including cancer. This chapter discusses the anticancer property of two herbal plants Aristolochia tagala Cham. and Curcuma caesia Roxb. in diethylnitrosamine-induced mouse liver cancer and describes the most probable molecular mechanisms of action of the metabolites present in these plants contributing to their anticancer effect.

Publisher

IGI Global

Reference196 articles.

1. A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis

2. Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements

3. Bioactive chemical constituents from Curcuma caesia Roxb. rhizomes and inhibitory effect of curcuzederone on the migration of triple-negative breast cancer cell line MDA-MB-231.;M.Al-Amin;Natural Product Research,2019

4. Antitumor activity of aristolochic acid isolated from Aristolochia talaga. Cham.;L. T.Angeles;Journal of Manila Medical Society,1970

5. A comparative study on in vitro antioxidant, anticancer and antimicrobial activity of the methanol extracts of the roots of four species of Aristolochia L. from southern Western Ghats of India.;E. S.Anilkumar;International Journal of Advanced Research,2014

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