This study investigates the application of the best available techniques (BAT) in enterprises. The article also analyzes the different approaches of the BAT, clearly stating how to apply the BAT and the conditions for using the BAT. The article also identifies and measures the factors affecting the application of BAT in enterprises. In addition, the paper also analyzes and measures the influence of BAT and other factors on the sustainable development of enterprises. The article shows that if using the BAT technique as an alternative technique while not needing to invest more in machinery and equipment, and resources, only changing the way of operation and processing process, enterprises can increase the level of environmental protection, make use of waste to complete the closed process, reduce costs, and increase profits. From that, the article proves that BAT is the best technique to prevent or reduce emissions and environmental impacts; businesses must use BAT if their activities are installations or manufacturing, export, and processing enterprises. The authors collect data from 192 manufacturing enterprises in six industries. The main data analysis method of this study is the structural equation modeling method (SEM). The article used AMOS software to evaluate and measure the influence of each factor on the application of BAT in the enterprise and the impact on the sustainability of the enterprise. BAT research has shown that the rational use of resources is essential. Measuring and recording information through the evaluation of techniques used in production also shows that we are disrupting the ecological environment without recreating it. We live by capital, not by added value, so environmental protection is necessary.