Affiliation:
1. Aristotle University of Thessaloniki, Greece & General Hospital “Agios Pavlos”, Thessaloniki, Greece
Abstract
Dementia is one of the most devastating disease of the elderly. Alzheimer's disease (AD) remain its most common cause. This chapter presents current data about AD risk factors, biomarkers, risk genes, available treatments. It also focuses on current and future perspectives about the use of personalized, non pharmaceutical computer- based intervation. The aim of this work is to propose that the knowledge of carring or not AD risk can be a guide for a personalized combination of brain training in preclinical stages of the disease in order to postpone or even cancel disease onset.
Reference127 articles.
1. Prediction of treatment response to rivastigmine in Alzheimer’s dementia.;G.Adler;Journal of Neurology, Neurosurgery, and Psychiatry,2004
2. The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
3. Alzheimer’s Disease: A Clinical Practice-Oriented Review
4. American College of Sports Medicine. (2005). Guidelines for graded exercise testing and exercise prescription. (Lea & Febiger, Ed.). Philadelphia: American Psychiatric Association.