Affiliation:
1. Haliç University, Turkey
2. Ege University, Turkey
3. Nişantaşı University, Turkey
Abstract
The inequality between the production of free radicals and reactive oxygen species, and their elimination by protective mechanisms, is defined as oxidative stress, which destroys cell components by creating various forms of free radicals that influence the pathogenesis of many diseases, such as cancer. Natural preservatives such as phytochemicals inhibit the production of free radicals and maintain oxidative balance. Lycopene, which has the high antioxidant ability, is one of these phytochemicals that reduces oxidative stress markers. Studies show a connection between a lycopene-rich diet in the prevention of oxidative stress harm. Lycopene is believed to minimize the risk of cardiovascular disease, cancer, metabolic syndrome, and obesity. In this chapter, the biochemical, structural, chemical, biological, and oxidative stress mechanisms of lycopene are evaluated, and the role of lycopene on cancer is discussed.