Bryo-Pharmaceuticals

Abstract

Because bryophytes are a promising source of a large number of secondary metabolites, they are used efficiently in surgical dressing, herbal medicines, antibiotics, and other pharmaceutical products. The advent of several biotechnological tools and their utilization in the exploitation of pharmaceuticals properties of bryophytes leads to a new era of bryo-pharmaceuticals. Nowadays, the biopharmaceutical productions using moss system are gaining importance over other plant systems because of their unique properties such as predominant haploid gametophytic stage, stable gene integration, efficient secretary signals, and large-scale production in bioreactors. Several researchers have established moss system as safe and efficient for the production of several complex modified recombinant pharmaceuticals under standard conditions. The moss Physcomitrella patens are extensively exploited and commercialized as a production host for production of several recombinant proteins, human growth factors, antibiotics, and its derivatives.