The intelligent lighting control system will unify the management of lighting equipment in outpatient buildings, inpatient buildings, and other buildings of the hospital, thereby improving the service quality of the hospital, providing a comfortable and relaxed working environment for medical staff, and providing a warm and comfortable treatment environment for patients. This project aims to develop a health rehabilitation environment lighting automation control system based on combining Zigbee Wide Ad Hoc Network and RFID (Radio Frequency Identification) technology. It can be customized according to the comfort needs of patients and can achieve lighting adjustments before the patient arrives. A PSO-based intelligent lighting control method has been proposed. To overcome the shortcomings of PSO such as being prone to local minima and premature convergence, a new PSO optimization method is proposed based on the inertia weight PSO and combined with genetic optimization theory. This method can not only learn experience from individuals in the group but also avoid the possibility of parent particles falling into local extremum. Compared with the original particle swarm optimization algorithm, the new particle swarm optimization algorithm can quickly find the optimal combination of lighting devices, improve computational efficiency by 6.208%, and also reduce the energy consumption of the calculated lighting devices, indicating the advantages of the new particle swarm optimization algorithm.