With the advent of the big data internet era, the corresponding multimedia technology is also developing. At the same time, as an important place for students to improve their cognitive level and expand their knowledge coverage, the construction of knowledge and information in university libraries will have an important impact on the growth of students and the development of the library itself. Big data not only brings specific challenges to the intelligent information construction of libraries, but also provides opportunities for the further development of intelligent information construction. Therefore, this paper aims to analyze the intelligent informatization construction of university libraries in the multimedia big data environment, make suggestions for the further development of library intelligent informatization construction, and provide reference materials for library intelligent informatization construction.