The Role of Perfusion Computed Tomography as a Predictor of Pancreatic Necrosis in Acute Pancreatitis

Author:

Klimova N. V.1ORCID,Darvin V. V.1ORCID,Bazhukhina I. V.1ORCID,Gaus A. A.1ORCID

Affiliation:

1. The Surgut State University; The Surgut Regional Clinical Hospital, Department of Radiological

Abstract

The presented article analyzes the data obtained as a result of the applied imaging methods of the study of 38 patients admitted to the surgical department of the Surgut Regional Clinical Hospital with suspicion of acute pancreatitis. The main criterion for inclusion in the study was the period from the onset of the initial symptoms of the disease, which did not exceed three days. In the hospital, all patients underwent perfusion computed tomography (PCT) in the first 3 days and subsequently, in accordance with national recommendations, multislice computed tomography (MSCT) with bolus intravenous contrast enhancement for 3–5 days. In 31,5 % of cases (12 out of 38 patients), a violation of the perfusion characteristics of the pancreatic parenchyma corresponding to ischemic tissue damage was diagnosed. MSCT with bolus intravenous contrast enhancement confirmed the presence of a formed zone of necrosis of the pancreatic tissue in 21 % of patients. In 10,5 % of cases, progression of ischemic damage to the pancreatic tissue was not revealed by MSCT, which was confirmed by further observation of this group of patients. Based on the study, conclusions were drawn about the ability of perfusion CT to serve as an effective predictor of pancreatic necrosis, which makes it possible to choose the optimal surgical tactics at the early stages of treatment of such patients.

Publisher

Central Research Institute of Radiation Diagnostics

Reference17 articles.

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