Author:
Jouyban Abolghasem,Fakhree Mohammad Amin Abolghasemi,Shayanfar Ali
Abstract
N-Methyl-2-pyrrolidone (NMP) or Pharmasolve is very strong solubilizing agent and it has important applications in different fields of industry. This review presents NMP physicochemical characteristics, application especially in pharmaceutical sciences, pharmacokinetic and toxicity. Characteristics of NMP such as physicochemical properties, solubilization efficacy, toxicity and adverse effects were compared with other common solvents used in the pharmaceutical industries. This review reveals that NMP is an acceptable pharmaceutical solvent and its efficacy, toxicity, and side effects are comparable with other common solvent.
Publisher
University of Alberta Libraries
Subject
Pharmaceutical Science,Pharmacology
Cited by
160 articles.
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