A Review Article on Analytical Method on Sitageliptin and Metformin-Reference-Cited by-同舟云学术

A Review Article on Analytical Method on Sitageliptin and Metformin

Published:2024-08-07 Issue: Volume: Page:74-78
ISSN:2581-9429
Container-title:International Journal of Advanced Research in Science, Communication and Technology
language:en
Short-container-title:IJARSCT

Author:

Divya Torne ¹,Purva Khatu ¹,Dr. Vaishali Pardeshi ¹,Supriya Bandichode ²,Mukund Matkar ¹,Prachi Bombale ³

Affiliation:

1. Abhinav Education Society Collage of Pharmacy, Narhe, Pune

2. Dr. Vittalrao Vikhe Patil College of Pharmacy,Viladghat, Amhadnagar

3. Shree Chankya Education Society Indira College of Pharmacy, Pune

Abstract

An overview about simultaneous estimation of the combination drugs, metformin and sitagliptin using RP-HPLC method. Reverse phase chromatography is the most commonly used separation technique in HPLC, common reasons being its simplicity, versatility and its ability to handle compounds of a diverse polarity and molecular mass.Good knowledge about different types of mobile phases and their combination are required for highly precise and accurate method development. The retention time and linearity of metformin and sitagliptin are found to be determined underdifferent chromatographic conditions such as column, mobile phase, elution mode, flow rate and wavelength detected using UV detector. In this article, we will be reviewing different developed methods for estimating the given combination drugs by RP-HPLC.

Publisher

Naksh Solutions

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