Medicinal Properties of Azadirachta Indica

Abstract

Neem oil (Azadirachta Indica A. Juss.) was tested for its antifungal properties against Drechsleraoryzae and Fusariumoxysporum and tenuis, and the results revealed that the active antifungal fraction is a combination of tetranortriterpenoids. [1Bandyopadhyay et al., Life Sciences, 71, 2845-2865, 2002] We have previously demonstrated that Neem (Azadirachtaindica) bark aqueous extract has effective antisecretory and antiulcer properties in animal models and has no significant side effect. Examining if neem bark extract had comparable antisecretory and antiulcer effects in human participants was the goal of the current study. [2] The antioxidant activity, total phenolic (TP), and total flavonoid (TF) contents of bark extracts from four different trees (Azadirachtaindica, Terminaliaarjuna, Acacia nilotica, and Eugenia jambolana Lam.) were assessed. The solvents used were 80% methanol, 80% ethanol, and 80% acetone (solvent:water, 80:20 v/v). By assessing reducing power, inhibiting peroxidation using the linoleic acid method, and DPPH scavenging activity, antioxidant activity (AA) was measured. Different bark extracts' TP, TF, suppression of linoleic acid oxidation, and DPPH• scavenging activity varied significantly (P 0.05). However, a slight difference in decreasing power was seen.[3].