Interval Versus Continuous Intradialytic Training on Muscle Quality Index and Functional Capacity in Hemodialysis Patients: a Prospective Randomized Clinical Study

Abstract

INTRODUCTION. Chronic kidney disease (CKD) is an important health well-being problem globally, with increasing incidence. That tends to create an “epidemic”. Generalized muscle weakness in hemodialysis patients typically affects the lower limbs and proximal muscles. Patients experience impaired endurance and quality of life. Exercise is prescribed for these individuals to improve their physical health and prevent disease consequences. AIM. To find out the effect of interval versus continuous intradialytic training on muscle quality index and functional capacity in Hemodialysis patients. MATERIALS AND METHODS. Sixty men with chronic renal insufficiency grade 5 on hemodialysis aged from 45 to 55 years were divided into two groups using computerized block randomization: Groups (A) and (B) each containing 30 patients. They underwent 8-week program of high intensity interval training (HIIT), moderate intensity continuous training (MICT) intradialytic pedaling exercise plus hemodialysis three times per week. Pre-test and post-test evaluations have been carried out for 6-minute walk test (6MWT) and muscle quality index (MQI) of all patients. RESULTS. Both groups had a significant positive improvement in MQI and 6MWT with different proportions, patients received high intensity interval intradialytic pedaling exercise had a slightly significant improvement in MQI compared to moderate intensity continuous training group. While, moderate intensity training group had a more significant improvement in 6MWT compared to high intensity training group. CONCLUSION. Both HIIT and MICT are realistic and good options for individuals with CKD and have parallel profits on functional capability and, skeletal muscle quality and overall quality of life.