Affiliation:
1. Tashkent Medical Academy
2. Shox International Hospital
3. Doktor Servis Clinic
Abstract
Aim. This study aimed to evaluate the therapeutic effiacy of two laser modalities, namely a 595-nm pulsed dye laser and a 755-nm long-pulse alexandrite laser, in the treatment of hemangiomas in patients with concurrent anemia.Methods. A total of 194 patients diagnosed with infantile hemangiomas, characterized by a thickness ranging from over 2 mm to under 8 mm, were included in this study. The patients were randomly assigned to two groups: the control group received treatment with the 595-nm pulsed dye laser, while the experimental group underwent sequential therapy, beginning with the 755-nm long-pulse alexandrite laser followed by the 595-nm pulsed dye laser.Results. In the control group, the overall treatment effiacy was 36.1 %. In contrast, the experimental group exhibited a signifiantly higher effiacy of 76.3 %. Statistical analysis of the abundance data was conducted using the Chi-square (X2) test, with results deemed statistically signifiant at a signifiance level of P < .05.Conclusion. Sequential therapy, which integrates both the 755-nm pulsed dye laser and the 595-nm pulsed dye laser, demonstrates remarkable effectiveness in treating hemangiomas, particularly in cases complicated by anemia.
Publisher
Center of Endourology Endocenter
Reference30 articles.
1. Wang PLJ, Yue W, Luo Y, ZK L, He J. Study on the diagnosis and differential diagnosis of contrast enhanced ultrasound for splenic hemangioma. China Continuing Med Educ. 2018;10:67—69.
2. Dickison P, Christou E, Wargon O. A prospective study of infantile hemangiomas with a focus on incidence and risk factors. Pediatr Dermatol. 2011 Nov-Dec;28(6):663—669. https://doi.org/10.1111/j.1525-1470.2011.01568.x
3. Beck DO, Gosain AK. G. A. The presentation and management of hemangiomas. Plast Reconstr Surg. 2009;123(6):181e—191e. doi:10.1097/PRS.0b013e3181a65c59
4. Gampper TJ, Morgan RF. Vascular anomalies: hemangiomas. PlastReconstr Surg. 2002;110(2):572—85. quiz 586; discussion 587—8. https://doi.org/10.1097/00006534-200208000-00032
5. Garden JM, Bakus AD, Paller AS. Treatment of cutaneous hemangiomas by the flshlamp-pumped pulsed dye laser: prospective analysis. J Pediatr. 1992;120(4):555—60. https://doi.org/10.1016/S0022-3476(05)82481-3