Whole-Blood RNA Profiles Associated with Pulmonary Arterial Hypertension and Clinical Outcome

Author:

Rhodes Christopher J.1,Otero-Núñez Pablo1,Wharton John1ORCID,Swietlik Emilia M.2,Kariotis Sokratis34,Harbaum Lars1,Dunning Mark J.5,Elinoff Jason M.6,Errington Niamh34,Thompson A. A. Roger4,Iremonger James4,Coghlan J. Gerry7,Corris Paul A.8,Howard Luke S.1,Kiely David G.4,Church Colin9,Pepke-Zaba Joanna10,Toshner Mark210,Wort Stephen J.1,Desai Ankit A.11,Humbert Marc121314,Nichols William C.15,Southgate Laura16ORCID,Trégouët David-Alexandre17,Trembath Richard C.18,Prokopenko Inga19,Gräf Stefan220ORCID,Morrell Nicholas W.2,Wang Dennis35,Lawrie Allan4,Wilkins Martin R.1ORCID

Affiliation:

1. National Heart and Lung Institute, Imperial College London, London, United Kingdom

2. Department of Medicine, University of Cambridge, Cambridge, United Kingdom

3. Sheffield Institute for Translational Neuroscience

4. Department of Infection, Immunity & Cardiovascular Disease, and

5. Sheffield Bioinformatics Core, The University of Sheffield, Sheffield, United Kingdom

6. Critical Care Medicine Department, NIH Clinical Center, Bethesda, Maryland

7. University College London, London, United Kingdom

8. Newcastle University, Newcastle upon Tyne, United Kingdom

9. University of Glasgow, Glasgow, United Kingdom

10. Royal Papworth Hospital, Cambridge, United Kingdom

11. Indiana University, Indianapolis, Indiana

12. Université Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France

13. Service de Pneumologie, Hôpital Bicêtre, Assistance Publique – Hôpitaux de Paris, Le Kremlin-Bicêtre, France

14. INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis Robinson, France

15. Division of Human Genetics, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio

16. Molecular and Clinical Sciences Research Institute, St. George’s University of London, London, United Kingdom

17. INSERM UMR_S 1219, Bordeaux Population Health Research Center, University of Bordeaux, Bordeaux, France

18. Division of Genetics and Molecular Medicine, King’s College London, London, United Kingdom

19. Department of Clinical and Experimental Medicine, University of Surrey, Guildford, United Kingdom; and

20. NIHR BioResource for Translational Research, Cambridge, United Kingdom

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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