Vascular–Parenchymal Cross-Talk Promotes Lung Fibrosis through BMPR2 Signaling

Author:

Yanagihara Toyoshi12ORCID,Tsubouchi Kazuya12,Zhou Quan1,Chong Michael3,Otsubo Kohei12,Isshiki Takuma14,Schupp Jonas C.56ORCID,Sato Seidai17,Scallan Ciaran1ORCID,Upagupta Chandak1,Revill Spencer1,Ayoub Anmar1,Chong Sy Giin1,Dvorkin-Gheva Anna8,Kaminski Naftali5ORCID,Tikkanen Jussi9,Keshavjee Shaf910ORCID,Paré Guillaume11124,Guignabert Christophe13,Ask Kjetil1ORCID,Kolb Martin R. J.1ORCID

Affiliation:

1. Firestone Institute for Respiratory Health, Research Institute at St. Joseph’s Healthcare, and

2. Department of Respiratory Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan;

3. Genetic and Molecular Epidemiology Laboratory, Population Health Research Institute, David Braley Cardiac, Vascular and Stroke Research Institute, Thrombosis and Atherosclerosis Research Institute, Department of Biochemistry and Biomedical Sciences,

4. Division of Respiratory Medicine, Toho University School of Medicine, Tokyo, Japan;

5. Section of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, Connecticut;

6. Department of Respiratory Medicine, Hannover Medical School, Biomedical Research in End-Stage and Obstructive Lung Disease Hannover, Member of the German Center for Lung Research, Hanover, Germany;

7. Department of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan;

8. McMaster Immunology Research Centre, Department of Medicine,

9. Toronto Lung Transplant Program, University Health Network, Toronto, Ontario, Canada;

10. Division of Thoracic Surgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada; and

11. Department of Pathology and Molecular Medicine, Michael G. DeGroote School of Medicine, and

12. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada;

13. INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis-Robinson, France

Funder

Canadian Institutes for Health Research

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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