Erythromycin or Clindamycin - is it Still an Empirical Therapy against Streptococcus agalactiae in Patients Allergic to Penicillin?

Author:

Leszczyński Piotr1,Sokół-Leszczyńska Beata2,Pietrzak Bronisława3,Sawicka-Grzelak Anna2,Wielgoś Mirosław3

Affiliation:

1. Department of Medical Microbiology, Warsaw Medical University of Warsaw, Warsaw, Poland; Hospital Infection Control Team, Infant Jesus University Hospital, Warsaw, Poland

2. Department of Medical Microbiology, Warsaw Medical University of Warsaw, Warsaw, Poland; Department of Medical Microbiology, Infant Jesus University Hospital, Warsaw, Poland

3. I Department of Obstetrics and Gynecology, Medical University of Warsaw, Warsaw, Poland

Abstract

Retrospective analysis of Streptococcus agalactiae antibiotic susceptibility isolated in 2010 - 2013 was performed. Penicillin was still the first-line antibiotic. Due to the high percentage of strains resistant to erythromycin and clindamycin empirical treatment with these antibiotics may not be effective. Lower resistance rate to erythromycin and clindamycin among strains isolated from infected pregnant women and newborns were observed than among strains isolated from samples from patients hospitalized in other departments (29% and 47% v. 46% and 63%). The increasing resistance rate might give a rise to a new epidemiological situation.

Publisher

Polish Society of Microbiologists

Subject

Microbiology (medical),Applied Microbiology and Biotechnology,General Medicine,Microbiology

Reference19 articles.

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3. Bigos M., M. Łysakowska and M. Wasiela. 2012. Perinatal infections of etiology Streptococcus agalactiae (in Polish). Post. Mikrobiol. 51(4): 299–308.

4. Brown H.L., H.K. Ahmadzia and R.P. Heine. 2013. GBS Screening: An update on guidelines and methods. http://contemporaryobgyn.modernmedicine.com/contemporary-obgyn/content/tags/bd-geneohm/gbs-screening-update-guidelines-and-methods, 2016.04.18.

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