Drug Compatibility in Treatment of Chronic Infectious Diseases-Reference-Cited by-同舟云学术

Drug Compatibility in Treatment of Chronic Infectious Diseases

Published:2021-09-28 Issue:5 Volume:11 Page:344-358
ISSN:2411-6564
Container-title:The Russian Archives of Internal Medicine
language:
Short-container-title:Arhivʺ vnutrennej mediciny

Author:

Bazrova E. S.¹^ORCID,Kaminskiy G. D.¹^ORCID,Ilchenko L. Yu.²^ORCID,Маtin A.³^ORCID,Nikitin I. G.⁴^ORCID

Affiliation:

1. Federal State Budgetary Institution «National Medical Research Center of Phthisiopulmonology and Infectious Diseases»

2. Federal State Budgetary Institution «National Medical Research Center of Phthisiopulmonology and Infectious Diseases»; Federal State Autonomous Institution «Treatment and Rehabilitation Center» Ministry of Health of Russia

3. Department of Hospital Therapy № 2 of the Federal State Autonomous Educational Institution of Higher Education «N.I. Pirogov Russian National Research Medical University» Ministry of Health of Russia

4. Federal State Autonomous Institution «Treatment and Rehabilitation Center» Ministry of Health of Russia; Department of Hospital Therapy № 2 of the Federal State Autonomous Educational Institution of Higher Education «N.I. Pirogov Russian National Research Medical University» Ministry of Health of Russia

Abstract

The article considers the features of pharmacotherapy of patients with chronic infectious diseases and co-morbidities in conditions of polypharmacy, the principles of drug metabolism, variants of adverse effects and drug-drug interactions, the possibilities of effective drug combinations. The purpose is to substantiate the possibility and emphasize the relevance of the additional search of the creation of the most optimal combinations of drugs for long-term and massive pharmacotherapy, that could be due to a beneficial drug-drug interaction, optimization of the regimen, route of drug administration and multitarget of the therapeutic effect, reduce the pharmacological load while maintaining the effectiveness of the treatment, increase patient adherence to drug therapy.

Publisher

Synapse, LLC

Subject

General Medicine

Reference36 articles.

1. Naranjo CA, Busto U, Sellers EM, et al. A method for estimating the probability of adverse drug reactions. Clin.Pharmacol.Ther. 1981; 30(2): 239-245. doi: 10.1038/clpt.1981.154

2. Rawlins M, Thompson W. Mechanisms of adverse drug reactions. Textbook of adverse drug reactions, ed. Davies D.M. New York. Oxford University Press. 1991; 18–45.

3. Edwards I.R, Aronson JK. Adverse drug reactions: definitions, diagnosis, and management. Lancet. 2000 Oct 7; 356(9237): 1255-9. doi: 10.1016/S0140-6736(00)02799-9.

4. Drug and Therapeutics Committee Training Course. Session 4. Assessing and Managing Medicine Safety Trainer’s Guide. WHO [Electronic resource]. URL: https://www.who. int/medicines/technical_briefing/tbs/04-PG_Dug-Safety_ final-08.pdf?ua=1#:~:text=Adverse%20drug%20reaction%20 (ADR)%E2%80%94,the%20modification%20of%20 physiological%20function.%E2%80%9D (date of application: 26.05.2021).

5. Defenitions, WHO [Electronic resource]. URL:https://www.who.int/medicines/areas/quality_safety/safety_ efficacy/trainingcourses/definitions.pdf (date of application: 26.05.2021).