Comparison of image quality and standardized uptake values (SUV) of two PET/CT imaging system using F-18 and Ga-68

Abstract

Abstract Both the Gemini TOF PET/CT and Biograph mCT flow PET/CT scanners are advanced imaging systems used in clinical settings for a range of applications, including oncology, neurology, and cardiology. Both the Gemini TOF PET/CT and Biograph mCT flow PET/CT scanners are advanced imaging systems used in clinical settings for a range of applications, including oncology, neurology, and cardiology. Both systems are capable of producing high quality images with good spatial resolution and contrast. However, there are some differences between the two systems that may impact image quality. The recovery coefficient (RC) is an important parameter that is used to evaluate the image quality and the accuracy and precision of PET/CT imaging systems. In the other hand, Standardized uptake value (SUV) is A frequently utilized quantitative measure in PET/CT imaging is the estimation of radiotracer uptake within a specified region of interest (ROI). SUV measurements are possible to be used to assess tumor metabolism and monitor treatment response. Several studies have evaluated the SUV and RC measurements using different radiotracers and scanner has been found to exhibit good accuracy and precision for both radiotracers. In this work we investigated the SUV and RC values of the Gemini TOF PET/CT and Biograph mCT flow PET/CT scanners by using F18 and Ga-68 and compared their values. Methods in this work, we analyzed images acquired using two distinct PET-CT scanners from two different manufacturers; Gemini TOF PET/CT (Philips Medical Systems) system and biograph mCT flow PET/CT system (Siemens Healthineers). we assessed the SUV values by using the PET-CT cylindrical image quality NEMA phantom that was filled with F-18 and Ga-68 while the image quality measured by employing the NEMA/International Electrotechnical Commission (IEC) Torso Phantom. Results We revealed that the RC values of F-18 using Gemini TOF PET/CT ranged from 0.02 to 0.03 for different sphere sizes, where they ranged from 0.005 to 0.015 for Ga-68 and when used Biograph mCT flow PET/CT scanner RC values of F-18 ranged from 0.025 to 0.05 and for Ga-68 ranged from 0.02 to 0.042. The first section in your paper