Antihyperglycemic Activities of Fermented Milk Enriched with Gembili (Dioscorea esculenta)

Abstract

Abstract Gembili is one variety of local tubers originating in Indonesia, where its utilization is not in its most use. This tuber has bioactive compounds such as dioscorin, diosgenin, inulin and water-soluble polysaccharides that function as immunomodulators, including those which prevents metabolic diseases such as hyperglycaemia. The addition of gembili tubers in fermented milk has more value and is an alternative nutraceutical food for people who need a healthy diet because it contains probiotics and bioactive components. This study aims to determine the antihyperglycemic activity of fermented milk enriched with gembili flour in animal models. Probiotics contained in fermented milk are Lactobacillus acidophilus, Lactobacillus plantarum and Streptococcus thermophilus. The experimental animals used in this study are healthy male white rats, not deformed, and had never been used in previous experiments. The animals in experiment were grouped into five treatment groups namely P1=negative control, P2=positive control, P3=1 ml/rat/day of fermented milk with the addition of gembili tubers, P4=2 ml/rat/day of fermented milk with the addition of gembili tubers, and P5=3 ml/rat/day of fermented milk with the addition of gembili tubers (P5). The results of this study prove that the addition of fermented milk enriched with gembili showed significant results (p<0.05) on the decrease in blood sugar levels with the highest decrease of 43.59% in the P5 group.