Environmental influence on the features of the formation of placental structures in cow

Abstract

Abstract Normal organization of placental structures at different stages of pregnancy is critical for the growth and development of the fetus. The aim of this study is to characterize the localization and ratio of epithelial and mesenchymal cells in the placenta of cows with physiological and complicated preeclampsia pregnancy using the immunohistochemical method. To date, it has been established that adverse environmental factors adversely affect the reproductive potential of animals regardless of their gender. The results of the study demonstrated that in the placenta of cows with the development of preeclampsia in the last stages of pregnancy, there was a significant decrease in the content of keratin filaments both in the trophoblasts of the villous tree of the fetus and in the epithelial cells of the maternal part in comparison with physiological values. In this case, the vimentin filaments also underwent partial degradation. Thus, the ratio of keratin and vimentin intermediate filaments can be used as a histological criterion for changes in the placental structures of cows during the development of preeclampsia.