Use of bacteriophage cocktails for ulcerative keratitis in horses, clinical and ophthalmological justification

Abstract

Abstract In the presented work, the authors assessed the possibility of using the drug from bacteriophage cocktails for the treatment of ulcerative keratitis in horses. The study was carried out on 30 horses (30 eyes), which were previously treated with antibiotics empirically, which resulted in the development of complications in the form of keratolysis and corneal abscess. On admission, horses were examined using a forehead magnifier and a portable slit lamp, and the cornea was stained with fluorescein to assess the diameter and depth of the corneal ulcer. For the treatment of horses with ulcerative keratitis and their complications, a bacteriophage was prescribed 3-5 times a day, depending on the severity of the disease. After using the bacteriophage drug, the authors noted a positive dynamics of the inflammatory process in a short period of time: vascularization and the formation of a granulation barrier with further restoration of the integrity of the cornea.