Biologically active plant-based mixture for the prevention and complex treatment of bronchopulmonary pathology

Abstract

Abstract The characteristics of the starting material and its active principles are given, which made it possible to scientifically substantiate the qualitative and quantitative composition of the prescription formula of a new specialized product. It is presented in the following biologically active additive form with directed functional properties, mg per one 0.6 g capsule: hydroxyl-cinnamic acids (kaftaric, chlorogenic, chicory), not less than 1.5; vitamin C – 60; rutine – 30; glycyrrhizic acid, not less than 2; zinc – 2.5; selenium – 0.0065. The hygienic quality of the developed product is shown, following regulated indicators of nutritional value defining its functional orientation are determined, mg/1 capsule: rutin – 30 (24-36); ascorbic acid – 60 (48-72); zinc – 2.5 (2.0 – 3.0); hydroxycinnamic acids, not less than 1.5; glycyrrhizic acid – 2.0. The regulated production parameters, which ensure the preservation of biologically active components of the formulation, are determined. The use of gelatin capsules allows combining prescription ingredients, protecting the contents from the effects of adverse factors, providing the necessary delivery speed to the target cell and localizing the action. Clinical trials of the effectiveness and functional properties of the developed product have been carried out by including it in the diet of children with acute respiratory diseases, such as bronchitis and pneumonia. The prescription of diet therapy provided an earlier return to normal life, cough and wheezing, swelling and hyperemia of the nasopharynx stopped faster. Research materials indicate the activation of immunity, increasing the body’s resistance to infection. The results obtained indicate the advisability of including the phytocomplex in the complex therapy of considered patients, and also using it as a prophylactic for weakened children.