The effects of PBB153 on the levels of E2, T and Vtg in zebrafish

Abstract

Abstract Polybrominated biphenyls (PBBs) are a class of industrial chemicals with the characteristics of persistent organic pollutant, which can cause pathological effects on the endocrine system such as the thyroid and adrenal glands. At the present study, the experiment was designed to obtain the effects of PBB153 on the levels of E2, T and Vtg in zebrafish. The zebrafish were exposed to increasing concentrations of PBB153 solution (0, 0.1 mg/L, 0.2 mg/L, 0.5 mg/L) for 21 days. The results showed that PBB153 had a certain inhibitory effect on the secretion of E2, T and Vtg in zebrafish. However, there are relatively few studies on the harm of PBBs and others environmental chemical pollutants to the endocrine system of aquatic organisms, and further research is needed.