The Role of Nano-Chitosan and some Antioxidants Associated with it in Improving Blood Profile and its Proteins in Laboratory Rats Exposed to Induced Oxidative Stress

Abstract

Abstract The study was conducted to show a possibility of improving the image blood and its proteins and antioxidants for each of vitamin-C, glutathione, coenzyme Q-10, and zinc associated with nano-chitosan It was found from the results of the study of the blood images that the criteria for the blood image for each of the numbers of white blood cells and the numbers of red blood cells And hemoglobin decreased significantly in a group of animals exposed to oxidative stress (T2), as it was at 5.2 ((×103/mm3), 5.1 ((×106/mm3, and 7.6 (g/dl). Compared with the control group (T1), whose numbers were 9.2 ((×103/mm3), 7.8 ((×106/mm3), and 15.1 (g/dl), respectively. Their numbers improved in animal groups for nanoparticles and their antioxidants. Also, the parameters of total protein, albumin, and globulin were significantly decreased in (T2) compared with their values in (T1). Its values improved after oral administration of chitosan nanoparticles and its conjugates after 28 days of dosing.