Acute Oral Toxicity Test of Nicotiana tabacum L. Bio-Oil Against Female Winstar Rats-Reference-Cited by-同舟云学术

Acute Oral Toxicity Test of Nicotiana tabacum L. Bio-Oil Against Female Winstar Rats

Published:2019-10-01 Issue:1 Volume:353 Page:012047
ISSN:1755-1307
Container-title:IOP Conference Series: Earth and Environmental Science
language:
Short-container-title:IOP Conf. Ser.: Earth Environ. Sci.

Author:

Andjani H N,Sentosa Y,Yati K,Fauzantoro A,Gozan M,Yoo Y J

Abstract

Abstract Tobacco plants are notably known for its pesticidal properties, particularly due to its nicotine content. In this study, Nicotiana tabacum L. bio-oil was obtained using pyrolysis technique. The safety of the bio-oil to be used as bioinsecticide was analyzed through acute oral toxicity test by administering 5000 mg bio-oil/kg body weight of female winstar rats that were analogous to humans. It was concluded that the bio-oil was not toxic due to absence of mortality and no significant change in the body weight and behavior of the rats.

Publisher

IOP Publishing

Subject

General Engineering

Link

https://iopscience.iop.org/article/10.1088/1755-1315/353/1/012047/pdf

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